The on-going COVID-19 pandemic has exposed vulnerabilities in the health systems all across the globe. On the other hand, the threat has also provided an extra-ordinary opportunity for a collective multi-sectoral response achieved with systems thinking and coordinated local execution. Most importantly, it has demonstrated the need for an effective digital backdrop that connects stakeholder organizations and ensures a rapid response towards mitigation of epidemics in a concerted manner. This has motivated the formation of the Precision Health, Artificial Intelligence for Healthcare theme of DRIIV.